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What if one of the most widely
used therapies in cancer treatment
could be made more effective?

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Our Mission

Our mission is simple: to amplify the effectiveness of the backbone of the most widely utilized cancer therapies, so treatments relied upon by millions of patients work better and can work effectively again when resistance appears.

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CV6-168

At CV6 Therapeutics, we are developing CV6-168, a first-in-class drug designed to amplify the activity of 5-fluorouracil (5-FU).

CV6-168 promotes uracil incorporation into DNA, increasing cancer cell DNA damage while stimulating innate immune responses. This approach is designed to enhance the performance of 5-FU, a backbone therapy used in millions of patients worldwide.

The program is currently advancing through clinical development.

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patients per year
More than 4.8 million patients each year receive 5-FU and related therapies, forming the backbone of treatment across major cancers including colorectal, breast, gastric, pancreatic, lung, and head and neck.
cases by 2040
Despite widespread use, resistance limits effectiveness over time. With global cancer incidence projected to exceed 30 million cases annually by 2040, improving these therapies represents a significant clinical opportunity.
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“”
Prof. Ruth Plummer, MD

If CV6-168 performs as expected, it could fundamentally change how we use 5-FU in cancer treatment.

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Test Press Release

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CV6 to Present Details of Ongoing Phase 1a Clinical Trial at 2024 ASCO Annual Meeting

CV6 to Present Details of Ongoing Phase 1a Clinical Trial at 2024 ASCO Annual Meeting

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